Actualités

 

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits

Sep 2, 2025 |

Marcy Belloy#, Benjamin A M Schmitt#, Florent H Marty , Charlotte Paut , Emilie Bassot , Amel Aïda , Marine Alis , Margot Zahm , Adeline Chaubet, Hugo Garnier , Thelma Flores-Aguilar , Elisa Roitg , Renzo Gutierrez-Loli , Sophie Allart , Romain Ecalard, Raphaël Boursereau , Gaëtan Ligat , Daniel Gonzalez-Dunia, Nicolas Blanchard , Elsa Suberbielle
Nat Neurosci, 2025 Aug 21.doi: 10.1038/s41593-025-02041-x. Online ahead of print.
Crédis photo : © Benjamin Schmitt & Elsa Suberbielle

Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice

Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice

Août 25, 2025 |

Aurora Pignata, David Frieser, Carmen Gonzalez-Fierro, Cheng-Chih Hsiao, Hendrik J. Engelenburg, Marine Alis, Ilan Fijalkow, Vincent Cazaentre, Lucie Nozeran, Romain Miranda-Capet, Eloïse Dufourd, Thaïs Vermeulen, Amel Aïda, Carole Le Coz, Klaas Van Gisbergen, Nicolas Blanchard, Jörg Hamann, Joost Smolders, Roland S. Liblau*, Frederick Masson*
23 juillet 2025, Sci. Transl. Med. 17, eadp8109 (2025)
Crédis photo : @Cheng-Chih Hsiao, Hendrik J. Engelenburg, Joost Smolders