Toulouse Institute for Infectious and Inflammatory Diseases

Immunology, Inflammation and Infectious diseases :

from basic to translational research

  Latest news

Role of Th17 cells in autoimmunity and tissue inflammation
Monday, November 3, 2025, at 11 AM - Pavillon Baudot - Prof Vijay Kuchroo
Role of ILC2s in the progression of allergic diseases
Thursday, November 13, 2025, at 13.30 PM - Green Meeting Room - Dr Itziar Martinez Gonzalez - Contact : Lilian Basso
Immunosenescence as the Central Mediator of Age-Related Vulnerability
Thursday, November 27, 2025, at 11 AM - Green Meeting Room - Dr Maria Mittelbrunn - Contact : Roland Liblau

Follicular regulatory T cells promote experimental autoimmune encephalomyelitis by supporting B cell egress from germinal centers

Fanny Martinez, Coline Cotineau, Julien Novarino, Cyrielle Bories, Louis Culie, Stephane Rodriguez, Corine Pérals, Simon Lachambre, Valérie Duplan-Eche, Florence Bucciarelli, Béatrice Pignolet, Roland S. Liblau, Laure Michel, Meryem Aloulou*#, Nicolas Fazilleau*#
Science Translational Medicine
27 Aug 2025, Vol 17, Issue 813

Maternal stress triggers early-life eczema through fetal mast cell programming

Serhan N, Abdullah NS, Gheziel N, Loste A, Ekren R, Labit E, Gonzalez AA, Oliva G, Tarot P, Petitfils C, Payros G, D’Avino P, Voisin A, Tinsley HFG, Gentek R, Brosseau C, Bodinier M, Reber L, Val P, Akdis CA, Mitamura Y, Andiappan AK, Chan JKY, Ginhoux F, François A, Cénac N, Basso L, Gaudenzio N
Nature. 2025 Aug 27. doi: 10.1038/s41586-025-09419-8. PMID: 40866704
Caption: skin apendages in grey, sensory neurons in cyan and activated mast cells in red
Copyright: ©Nadine Serhan

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits

Authors: Marcy Belloy#, Benjamin A M Schmitt#, Florent H Marty , Charlotte Paut , Emilie Bassot , Amel Aïda , Marine Alis , Margot Zahm , Adeline Chaubet, Hugo Garnier , Thelma Flores-Aguilar , Elisa Roitg , Renzo Gutierrez-Loli , Sophie Allart , Romain Ecalard, Raphaël Boursereau , Gaëtan Ligat , Daniel Gonzalez-Dunia, Nicolas Blanchard , Elsa Suberbielle
Nat Neurosci, 2025 Aug 21.doi: 10.1038/s41593-025-02041-x. Online ahead of print.

Copyright : ©Benjamin Schmitt & Elsa Suberbielle

Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice

Authors: Aurora Pignata, David Frieser, Carmen Gonzalez-Fierro, Cheng-Chih Hsiao, Hendrik J. Engelenburg, Marine Alis, Ilan Fijalkow, Vincent Cazaentre, Lucie Nozeran, Romain Miranda-Capet, Eloïse Dufourd, Thaïs Vermeulen, Amel Aïda, Carole Le Coz, Klaas Van Gisbergen, Nicolas Blanchard, Jörg Hamann, Joost Smolders, Roland S. Liblau*, Frederick Masson*
23 July 2025, Sci. Transl. Med. 17, eadp8109 (2025)
Copyright : ©Cheng-Chih Hsiao, Hendrik J. Engelenburg, Joost Smolders

Two INFINITY researchers laureates of the BMS Foundation’s 2025 Call for Projects

Dr Isabelle LAMSOUL and Dr Sophie LAFFONT-PRADINES are winners of the BMS Foundation’s 2025 Call for Projects for research in immuno-oncology Congratulations to Isabelle and Sophie!

Charlène Martin wins a 2025 thesis prize from the Société Française de Virologie (French Virology Society)

Charlène Martin, a former doctoral student in the ViNeDys 7 team, was awarded a thesis prize (‘Other viruses’ category, 2nd prize) at the recent French-speaking virology days, held in Lyon from 23 to 25 April 2025. Congratulations to Charlène!

Toulouse researchers have identified a new target for treating asthma

© Photo DDM/Frédéric Scheiber Link to the article from La Dépêche du Midi Link to the scientific article from CNRS

Chloé Dias – Thesis prize 2024 !

On the occasion of the 7th FSEV Meeting (French Society for Extracellular Vesicles) held in Strasbourg from November 4 to 6, 2024, Chloé DIAS, postdoctoral researcher under the supervision of Stéphane Trudel and Jérôme Ausseil, had the honor of winning the 2024 Thesis...

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